Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Dicyclohexylcarbodiimide → 4-Oxo-decanoic acid 3,7-dimethyl-oct-2,6-dienyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Dicyclohexylcarbodiimide | HCID 10868 | — |
| 반응물 | 4-Pyrrolidinopyridine | HCID 75567 | — |
| 반응물 | 4-Oxo capric acid | HCID 538647 | — |
| 반응물 | Geraniol | HCID 637566 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | 4-Oxo-decanoic acid 3,7-dimethyl-oct-2,6-dienyl ester | HCID 53970489 | 218.8% |
반응 단계
A solution of 5.2 g 4-oxo-decanoic acid, 13.5 g geraniol, 17.5 g N,N′-dicyclohexyl-carbodiimide and 1.0 g 4-pyrrolidinopyridine in 250 ml of dichloromethane was stirred for 24 hours at room temperature. The precipitate was filtered off, the filtrate was diluted with ether, washed with aqueous hydrochloric acid, saturated NaHCO3 and brine. The organic phase was dried, filtered and evaporated to dryness. The resulting oil-cristall mixture was purified by chromatography to yield 19.7 g of a colourless oil.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06369248B1 |
| 출처 데이터셋 | uspto-grants-2002_04 |
| ORD ID | ord-a7d181d12292442e96cf23e8a9f9a07b |
| 출처 메모 | uspto-grants-2002_04 |