참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | (-)-Secoisolariciresinol | HCID 65373 | — |
| 반응물 | Triphenyl phosphine chloride | HCID 22619264 | — |
| 용매 | Acetonitrile | HCID 6342 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | 3,4-Divanillyltetrahydrofuran | HCID 182210 | 81% |
반응 단계
(−) secoisolariciresinol (100 mg,) was dissolved in THF (5 ml) and to it was added a solution of triphenyl phosphine chloride in acetonitrile (1 ml) and the mixture was stirred at 0-80° C. for 1-10 hours. After completion of the reaction, the reaction mixture was concentrated under vacuum and the residue thus obtained was chromatographed over florosil column. Elution of the column with 30% EtOAC in pet. ether gave (−-3,4-divanillyl tetrahydrofuran (77 mg), m.p. 114-116° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US06372922B1 |
|---|
| 출처 데이터셋 | uspto-grants-2002_04 |
|---|
| ORD ID | ord-9df280bb6dd545bfbb36d42525c2a215 |
|---|
| 출처 메모 | uspto-grants-2002_04 |
|---|
