Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methanol → Methyl 3-iodo-5-nitrobenzoate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methanol | HCID 887 | — |
| 반응물 | Thionyl Chloride | HCID 24386 | — |
| 반응물 | 3-Iodo-5-nitrobenzoic acid | HCID 80580 | — |
| 생성물 | Methyl 3-iodo-5-nitrobenzoate | HCID 7020599 | 99% |
반응 단계
To a solution of 3-iodo-5-nitrobenzoic acid (20.00 g, 0.068 mol) in methanol (50 mL) was added SOCl2 (5.45 mL, 0.075 mol) at 0° C. The reaction mixture was allowed to warm to room temperature and was then heated to reflux for 2 hours. The reaction was cooled and solvent was removed in vacuo to afford 3-Iodo-5-nitro-benzoic acid methyl ester as light yellow solid (20.67 g, 99%). MS (M+H)=309.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08846945B2 |
| 출처 데이터셋 | uspto-grants-2014_09 |
| ORD ID | ord-5dc54d7bf03846c3958777d13f6cc5c9 |
| 출처 메모 | uspto-grants-2014_09 |