Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2,3-Diaminobenzoic acid → 2-(2-(difluoromethyl)-4-(2-morpholinoethoxy)phenyl)-1H-benzo[d]imidazole-7-carboxylic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2,3-Diaminobenzoic acid | HCID 198069 | — |
| 반응물 | 2-(Difluoromethyl)-4-(2-morpholinoethoxy)benzaldehyde | HCID 83854627 | — |
| 생성물 | 2-(2-(difluoromethyl)-4-(2-morpholinoethoxy)phenyl)-1H-benzo[d]imidazole-7-carboxylic acid | HCID 178524245 | 48% |
반응 단계
2,3-Diaminobenzoic acid (1; 222 mg, 1.5 mmol) and the corresponding 2-(difluoromethyl)-4-(2-morpholinoethoxy)benzaldehyde 124 were subjected to the same general procedure detailed above to afford 2-(2-(difluoromethyl)-4-(2-morpholinoethoxy)phenyl)-1H-benzo[d]imidazole-7-carboxylic acid 125 (300 mg, 48%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08846947B2 |
| 출처 데이터셋 | uspto-grants-2014_09 |
| ORD ID | ord-0a317f28990942a3b134fb224e52afbd |
| 출처 메모 | uspto-grants-2014_09 |