Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Phenethylamine, m-trifluoromethyl- → HCID 69342790, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Phenethylamine, m-trifluoromethyl- | HCID 104223 | — |
| 반응물 | Sodium borohydride | HCID 4311764 | — |
| 반응물 | (4-Cyclopropylbenzyl)-[2-(4-fluoro-3-trifluoromethylphenyl)-ethyl]-amine | HCID 69342889 | — |
| 반응물 | 4-(1-Methoxycyclopropyl)-benzaldehyde | HCID 86093727 | — |
| 생성물 | HCID 69342790 | HCID 69342790 | — |
반응 단계
The title compound was synthesized in analogy to (4-cyclopropylbenzyl)-[2-(4-fluoro-3-trifluoromethylphenyl)-ethyl]-amine (described in example S53) using 4-(1-methoxy-cyclopropyl)-benzaldehyde (105 mg, 0.60 mmol), 2-(3-trifluoromethylphenyl)-ethylamine (113 mg, 0.60 mmol) and sodium borohydride (34 mg, 0.89 mmol). The desired product was isolated without further purification as a colorless oil. MS (ISP) 350.4 (M+H)+.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07259183B2 |
| 출처 데이터셋 | uspto-grants-2007_08 |
| ORD ID | ord-265f379c2c0b448885da0caac7c72715 |
| 출처 메모 | uspto-grants-2007_08 |