Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Aminophenol → Benzenamine, 4-(2-benzoxazolyl)-
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Aminophenol | HCID 5801 | — |
| 반응물 | O-Phenylenediamine | HCID 7243 | — |
| 반응물 | 2-Aminothiophenol | HCID 8713 | — |
| 생성물 | Benzenamine, 4-(2-benzoxazolyl)- | HCID 88733 | — |
| 생성물 | 2-(4-Aminophenyl)benzothiazole | HCID 234475 | — |
| 생성물 | 4-(1H-1,3-benzodiazol-2-yl)aniline | HCID 345677 | — |
반응 단계
In Scheme 4a, a 2-aminophenol, 2-aminothiophenol or 2-aminoaniline derivative 4a is heated with an appropriately substituted 4-aminobenzoic acid 4b in polyphosphoric acid at about 170° C. to 200° C. for 4–10 hr, preferably 190° C. for 6 hr, to yield the corresponding 4-benzoxazol-2-yl-phenylamine, 4-benzothiazol-2-yl-phenylamine, or 4-benzimidazol-2-yl-phenylamine derivatives 1e4.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07262318B2 |
| 출처 데이터셋 | uspto-grants-2007_08 |
| ORD ID | ord-7d98f82e19554deb993c9bf779e78a0e |
| 출처 메모 | uspto-grants-2007_08 |