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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 857068생성일: 2026년 10월 24일

Water → N-[(4-benzothiazol-2-yl)phenyl]-4-methylbenzenesulfonamide

https://huagongshe.com/ko/reaction/857068

반응식

참여 물질

역할이름HCID투입량
반응물WaterHCID 962—
반응물4-Toluenesulfonyl chlorideHCID 7397—
반응물2-(4-Aminophenyl)benzothiazoleHCID 234475—
용매PyridineHCID 1049—
생성물N-[(4-benzothiazol-2-yl)phenyl]-4-methylbenzenesulfonamideHCID 4380499—

반응 단계

To 2-(4-aminophenyl)benzothiazole (0.5 g, 2.2 mmol) in pyridine (6 mL) is added para-toluenesulphonyl chloride (0.506 g, 2.7 mmol, 1.5 eq.) in pyridine (4 mL). The reaction mixture is heated at reflux for 10 mins, then cooled and water (10 mL) added. The white precipitate formed is collected on a filter, washed with water, and dried under vacuum to give N-[4-(benzothiazol-2-yl)phenyl]-4-methylbenzenesulfonamide as a white solid.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US07144893B2
출처 데이터셋uspto-grants-2006_12
ORD IDord-8126ba76e63641bbac8c1bf34ce2e323
출처 메모uspto-grants-2006_12