Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-(4-Methylphenyl)propan-2-amine → N-[1-(4-Methylphenyl)-1-methylethyl]-3-cyanoandrosta-3,5-diene-17beta-carboxamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-(4-Methylphenyl)propan-2-amine | HCID 584050 | — |
| 반응물 | S-2pyridyl 3-cyanoandrosta-3,5-diene-17beta-thiocarboxylate | HCID 15380265 | — |
| 생성물 | N-[1-(4-Methylphenyl)-1-methylethyl]-3-cyanoandrosta-3,5-diene-17beta-carboxamide | HCID 67646695 | 88% |
반응 단계
Following a procedure similar to that described in Example 3(b), but using S-2-pyridyl 3-cyanoandrosta-3,5-diene-17β-thiocarboxylate [prepared as described in Example 3(a)] and 1-(4-methylphenyl)-1-methylethylamine (prepared as described in Preparation 10h) as starting materials, in relative proportions similar to those used in that Example, the title compound was obtained in a yield of 88%.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05717088 |
| 출처 데이터셋 | uspto-grants-1998_02 |
| ORD ID | ord-9aac0f34f0664b8ea0821f37fb47a703 |
| 출처 메모 | uspto-grants-1998_02 |