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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 863348생성일: 2026년 10월 24일

4-nitrobenzyl (1R, 5S,6S)-2-(2-diethylcarbamoylphenylsulfinyl)-1-methyl-6-[1(R)-t-butyldimethylsilyloxyethyl]-1-carbapen-2-em-3-carboxylate → 4-Nitrobenzyl (1R, 5S,6S)-2-[2-(1-perhydroazepinylcarbonyl)phenylthio]-1-methyl-6-[1(R)-t-butyldimethylsilyloxyethyl]-1-carbapen-2-em-3-carboxylate

https://huagongshe.com/ko/reaction/863348

반응식

참여 물질

역할이름HCID투입량
반응물4-nitrobenzyl (1R, 5S,6S)-2-(2-diethylcarbamoylphenylsulfinyl)-1-methyl-6-[1(R)-t-butyldimethylsilyloxyethyl]-1-carbapen-2-em-3-carboxylateHCID 11028830—
반응물2-(1-Perhydroazepinylcarbonyl)phenylmercaptanHCID 11770438—
생성물4-Nitrobenzyl (1R, 5S,6S)-2-[2-(1-perhydroazepinylcarbonyl)phenylthio]-1-methyl-6-[1(R)-t-butyldimethylsilyloxyethyl]-1-carbapen-2-em-3-carboxylateHCID 1053268995%

반응 단계

Following a procedure similar to that described in Example 18, but using 4-nitrobenzyl (1R,5S,6S)-2-(2-diethylcarbamoylphenylsulfinyl)-1-methyl-6-[1(R)-t-butyldimethylsilyloxyethyl]-1-carbapen-2-em-3-carboxylate (prepared as described in Example 39) and 2-(1-perhydroazepinylcarbonyl) phenylmercaptan as starting materials, in relative proportions similar to those used in that Example, the title compound was obtained in a yield of 95%. This compound was found to be the same as the compound prepared as described in Example 36 and had the same physicochemical properties.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US05719275
출처 데이터셋uspto-grants-1998_02
ORD IDord-53066f2f871547c1bef5afa47212d7e7
출처 메모uspto-grants-1998_02