Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Potassium Carbonate → [3-(3-Thieno[2,3-d]isoxazol-3-yl-phenoxy)-propyl]-thiophen-3-yl-methylamine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | 3-Thiophenemethylamine | HCID 2776381 | — |
| 반응물 | 3-[3-(3-Chloro-propoxy)-phenyl]-thieno[2,3-d]isoxazole | HCID 21983556 | — |
| 반응물 | 3-[3-(3-Bromo-propoxy)phenyl]-thieno[2,3-d]isoxazole | HCID 21983559 | — |
| 생성물 | [3-(3-Thieno[2,3-d]isoxazol-3-yl-phenoxy)-propyl]-thiophen-3-yl-methylamine | HCID 69652986 | 86% |
반응 단계
The title compound is prepared from a mixture of 3-[3-(3-bromo-propoxy)-phenyl]-thieno[2,3-d]isoxazole, 3-[3-(3-chloro-propoxy)-phenyl]-thieno[2,3-d]isoxazole, 3-thiophenemethylamine and potassium carbonate essentially as described above in example 4. Combine the appropriate fractions and concentrate to give the title compound (0.32 g, 86% Yield) as an oil. Purity by LC/MS (APCI)=98%, [M+H]+=371 m/e.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07091199B1 |
| 출처 데이터셋 | uspto-grants-2006_08 |
| ORD ID | ord-92bcf849b3e149aea25a639e139f430f |
| 출처 메모 | uspto-grants-2006_08 |