Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Dimethyl acetylenedicarboxylate → Methyl [3-cyclohexyl-2-(cyclohexylimino)-4-oxo-5-thiazolidinylidene]acetate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Dimethyl acetylenedicarboxylate | HCID 12980 | — |
| 반응물 | Dicyclohexylthiourea | HCID 727200 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | Methyl [3-cyclohexyl-2-(cyclohexylimino)-4-oxo-5-thiazolidinylidene]acetate | HCID 3967510 | 76.8% |
반응 단계
A mixture of N,N'-dicyclohexylthiourea (10.0 g, 42 mmoles) and dimethylacetylenedicarboxylate (7.8 g, 55 mmoles) in methanol (100 mls) is stirred at room temperature for 16 hours, then warmed on a steambath for 45 minutes and cooled. The precipitate is filtered off, rinsed with cold methanol and dried. This gave the product as white crystals, (11.3 g), mp 97°-98° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04775677 |
| 출처 데이터셋 | uspto-grants-1988_10 |
| ORD ID | ord-509049bbe55149f198cffb6800332198 |
| 출처 메모 | uspto-grants-1988_10 |