Sulfuric Acid → HCID 399283, 화합물

HRID 868780

반응식

HRID 868780 반응식
[S:1]1[CH:5]=[C:4]([C:6]([O:8]CC)=O)[C:3]([C:11]([O:13]CC)=O)=[CH:2]1.[O-][CH2:17]C.[Na+].C(OCC)(=O)C.S(=O)(=O)(O)O>O>[CH:5]1[S:1][CH:2]=[C:3]2[C:11](=[O:13])[CH2:17][C:6](=[O:8])[C:4]=12

참가 물질

6

반응물 4

HCID 1118Sulfuric AcidHCID 8857Ethyl AcetateHCID 2723922Sodium ethoxideHCID 12197673Diethyl thiophene-3,4-dicarboxylate

생성물 1

HCID 399283HCID 399283, 화합물

시약·촉매·용매 1

HCID 962Water용매

실험 절차

In a dry 3-neck flask with an argon inlet and a water condenser, diethyl thiophene-3,4-dicarboxylate (3.7 g, 16.2 mmol) is mixed with sodium ethoxide (1.1 g, 16.2 mmol). After heating to 100° C. ethyl acetate (1.4 g, 16.2 mmol) is added through syringe pump over one hour. The mixture was further heated for a few hours. The residue was redissolved in water at 70° C. and concentrated sulfuric acid is added (1 mL). The mixture is heated at this temperature for one hour to ensure complete decarboxylation.

후처리

  1. additionis added through syringe pump over one hour
  2. temperatureThe mixture was further heated for a few hours
  3. temperatureThe mixture is heated at this temperature for one hour

출처 및 근거

ORD 기록
ord-2b6180bbf40a429c873ccf89181867b6
출처 데이터셋
uspto-grants-2015_03
특허 번호
US08968885B2

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