참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | 4-Bromophenacyl bromide | HCID 7454 | — |
| 반응물 | Triethylamine | HCID 8471 | — |
| 반응물 | Benzenemethanamine, 2,4-dichloro-N-methyl- | HCID 485424 | — |
| 용매 | 1,4-Dioxane | HCID 31275 | — |
| 생성물 | 1-(4-Bromophenyl)-2-((2,4-dichlorobenzyl)(methyl)amino)ethanone | HCID 22386828 | — |
반응 단계
Into a 250-mL 3-necked round-bottom flask purged and maintained with an inert atmosphere of nitrogen, was placed a solution of 2-bromo-1-(4-bromophenyl)ethanone (9.3 g, 33.45 mmol, 1.00 equiv) in dioxane (100 mL), triethylamine (5.0 g, 1.50 equiv), and (2,4-dichlorophenyl)-N-methylmethanamine (6.4 g, 33.68 mmol, 1.00 equiv). The resulting solution was stirred for 2 h at 25° C. The solids were filtered out. The filtrate was used for next step directly.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| 특허 번호 | US08969377B2 |
|---|
| 출처 데이터셋 | uspto-grants-2015_03 |
|---|
| ORD ID | ord-8810e10074554d5fa7dd0a3d3a8fcd97 |
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| 출처 메모 | uspto-grants-2015_03 |
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