Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-Fluorophenylboronic acid → HCID 21933850, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-Fluorophenylboronic acid | HCID 285645 | — |
| 반응물 | 4-Chloro-5-methoxy-2-phenyl-3(2H)-pyridazinone | HCID 349842 | — |
| 생성물 | HCID 21933850 | HCID 21933850 | 96% |
반응 단계
The 2-phenyl-4-chloro-5-methoxy-3(2H)-pyridazinone product was coupled with 4-fluorophenylboronic acid according to the method of Example 6 to provide 2-phenyl-4-(4-fluorophenyl)-5-methoxy-3(2H)-pyridazinone (yield: 1.1 g; 96%). 1H NMR (300 MHz, CDCl3) δ 4.00 (s, 3H), 7.10 (t, J=9 Hz, 2H), 7.45 (m, 3H), 7.60 (m, 4H), 8.06 (s, 1H). MS (DCI/NH3) m/z 297 (M+H)+.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07001895B2 |
| 출처 데이터셋 | uspto-grants-2006_02 |
| ORD ID | ord-8c4fe966344145fbb7521257ec54c6f4 |
| 출처 메모 | uspto-grants-2006_02 |