Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Water → 5-Chloro-2-hydroxy-3-methoxybenzaldehyde
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Water | HCID 962 | — |
| 반응물 | o-Vanillin | HCID 8991 | — |
| 반응물 | Sulfuryl chloride | HCID 24648 | — |
| 용매 | Toluene | HCID 1140 | — |
| 생성물 | 5-Chloro-2-hydroxy-3-methoxybenzaldehyde | HCID 5151086 | — |
반응 단계
A solution of sulfuryl chloride (15 mL, 190 mmol) in toluene (20 mL) is added dropwise over 1.5 h to a solution of o-vanillin (25.0 g, 164 mmol) in toluene (90 mL) and the reaction is then stirred 16 h. Water (30 mL) is added over 10 minutes with ice-bath cooling. The solid is filtered, washed with water and dried to provide the title compound. MS (EI) 186 (M)+.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07005440B1 |
| 출처 데이터셋 | uspto-grants-2006_02 |
| ORD ID | ord-17aa28f080b149d99a1ef1821d5e4992 |
| 출처 메모 | uspto-grants-2006_02 |