Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Sodium hydride → Diethyl 3-methoxyphenylmethoxymethylphosphonate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Sodium hydride | HCID 24758 | — |
| 반응물 | 3-Methoxybenzyl alcohol | HCID 81437 | — |
| 반응물 | (Diethoxyphosphoryl)methyl trifluoromethanesulfonate | HCID 11833487 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | Diethyl 3-methoxyphenylmethoxymethylphosphonate | HCID 57457789 | — |
반응 단계
A mixture of 3-methoxybenzyl alcohol (1 mmol) and sodium hydride (1.5 mmol) in 5 mL DMF was stirred at rt for 1 h and then added via cannula to a solution of diethylphosphonomethyl triflate (1 mmol) in 5 mL of DMF and the resulting mixture stirred at rt for 16 h. Extraction and chromatography provided diethyl 3-methoxyphenylmethoxymethylphosphonate as an oil.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06919322B2 |
| 출처 데이터셋 | uspto-grants-2005_07 |
| ORD ID | ord-00768cb80cee40e1a1d29555ffc8d90e |
| 출처 메모 | uspto-grants-2005_07 |