Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Pyridine → Piperidine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Pyridine | HCID 1049 | — |
| 반응물 | Acetonitrile | HCID 6342 | — |
| 반응물 | Nitromethane | HCID 6375 | — |
| 반응물 | Benzenepropanenitrile, 4-amino-beta-oxo- | HCID 96920 | — |
| 용매 | Isopropanol | HCID 3776 | — |
| 생성물 | Piperidine | HCID 8082 | — |
| 생성물 | Dabco | HCID 9237 | — |
| 생성물 | 1,1,3,3-Tetramethylguanidine | HCID 66460 | — |
반응 단계
In accordance with the second procedure, the 4-alkanesulfonaminobenzoylacetonitrile is first prepared by reaction of an alkanesulfonylchloride with 4-amino-benzoylacetonitrile at room temperature in dry pyridine. This product is in turn reacted with a dialkylaminobenzaldehyde at reflux temperature in isopropyl alcohol, acetonitrile, nitromethane, or a similar polar solvent and in the presence of a catalytic amount of piperidine, or another catalyst of comparable basicity such as tetramethylguanidine or triethylenediamine, to yield the desired dye.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04420555 |
| 출처 데이터셋 | uspto-grants-1983_12 |
| ORD ID | ord-f9c4427952c3423b91e2d1a258b32f99 |
| 출처 메모 | uspto-grants-1983_12 |