Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-(2-bromo-cyclopent-2-enyl)-N,N-dimethyl-acetamide → 2-(2-Bromo-cyclopent-2-enyl)-ethanol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-(2-bromo-cyclopent-2-enyl)-N,N-dimethyl-acetamide | HCID 21986069 | — |
| 반응물 | Lithiumtriethylborohydride | HCID 23664628 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | 2-(2-Bromo-cyclopent-2-enyl)-ethanol | HCID 21986094 | 58% |
반응 단계
2-(2-Bromo-cyclopent-2-enyl)-N,N-dimethyl-acetamide (Intermediate FOUR1) (1.93 g, 8.3 mmol) in THF (50 mL) was reacted with lithium triethylborohydride (19 mL, 1 M in THF) at 0° C. for 1 h. The mixture was treated with an aqueous work-up and the resultant alcohol was purified by column chromatography to give 0.92 g of 2-(2-bromo-cyclopent-2-enyl)-ethanol Intermediate FIVE1.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07091232B2 |
| 출처 데이터셋 | uspto-grants-2006_08 |
| ORD ID | ord-08e867a4674e4c02a3f0795e25c3850a |
| 출처 메모 | uspto-grants-2006_08 |