Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
(Butylamino)acetonitrile → (RS)-N-butyl-4-chloro-N-(cyanomethyl)-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidine-7-carboxamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | (Butylamino)acetonitrile | HCID 76373 | — |
| 반응물 | HCID 17990077 | HCID 17990077 | — |
| 생성물 | (RS)-N-butyl-4-chloro-N-(cyanomethyl)-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidine-7-carboxamide | HCID 90015777 | — |
반응 단계
300 mg (1.12 mmol) (RS)-4-chloro-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidine-7-carboxylic acid (prepared according to intermediate example 31b) were transformed in analogy to example 3 using (butylamino)acetonitrile to give after working up and purification 280 mg (69%) of the title compound.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09296757B2 |
| 출처 데이터셋 | uspto-grants-2016_03 |
| ORD ID | ord-9388160c06b84dc1a83c39fb4d8b83b9 |
| 출처 메모 | uspto-grants-2016_03 |