Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Triethyl phosphite → Diethyl (2,3,3-trifluro-2propenyl)phosphonate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Triethyl phosphite | HCID 31215 | — |
| 반응물 | 1-Propene, 3-bromo-1,1,2-trifluoro- | HCID 10631079 | — |
| 생성물 | Diethyl (1,1,2-trifluoro-2-propenyl)phosphonate | HCID 53986716 | 11% |
| 생성물 | Diethyl (2,3,3-trifluro-2propenyl)phosphonate | HCID 54339468 | 14% |
반응 단계
A solution of 2,3,3-trifluoro-2-propenyl bromide (5.25 g, 30 mmol) and triethyl phosphite (4.15 g, 25 mmol) in acetonltrile (15 mL) was heated at reflux for overnight. The residue obtained after evaporation of the solvent was chromatographed over silica gel (hexanes/ethyl acetate/ethanol, 80/20/1) to give diethyl (1,1,2-trifluro-2-propenyl)phosphonate (0.8 g, 11%) and diethyl (2,3,3-trifluro-2-propenyl)phosphonate (1.0 g, 14%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05723470 |
| 출처 데이터셋 | uspto-grants-1998_03 |
| ORD ID | ord-69bdc7c6a2fb4d4987a431b8e37f7f33 |
| 출처 메모 | uspto-grants-1998_03 |