돌아가기
Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 9678생성일: 2026년 10월 24일

{3-Methyl-5-[4-(trifluoromethoxy)phenyl]thien-2-yl}methanol → {5-[2-Fluoro-4-(trifluoromethyl)phenyl]-3-methylthien-2-yl}methanol

https://huagongshe.com/ko/reaction/9678

반응식

참여 물질

역할이름HCID투입량
반응물{3-Methyl-5-[4-(trifluoromethoxy)phenyl]thien-2-yl}methanolHCID 21986356—
반응물({5-[2-Fluoro-4-(trifluoromethyl)phenyl]-3-methylthien-2-yl}methoxy)(triisopropyl)silaneHCID 69591680—
생성물{5-[2-Fluoro-4-(trifluoromethyl)phenyl]-3-methylthien-2-yl}methanolHCID 21986424—

반응 단계

The title compound was prepared using a method analogous to that used for the preparation of {{3-methyl-5-[4-(trifluoromethoxy)phenyl]thien-2-yl}methanol (intermediate 118) using ({5-[2-fluoro-4-(trifluoromethyl)phenyl]-3-methylthien-2-yl}methoxy)(triisopropyl)silane (intermediate 123).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US07091237B2
출처 데이터셋uspto-grants-2006_08
ORD IDord-ab42de0f5742458eae6065e2d141c665
출처 메모uspto-grants-2006_08