Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Dimethylformamide dimethyl acetal → 96605-61-7
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Dimethylformamide dimethyl acetal | HCID 78373 | — |
| 반응물 | 3'-Acetamidoacetophenone | HCID 346202 | — |
| 용매 | Diethyl Ether | HCID 3283 | — |
| 용매 | Ethyl Acetate | HCID 8857 | — |
| 생성물 | 96605-61-7 | HCID 53412415 | — |
반응 단계
A mixture of 3-acetamidoacetophenone 7 (20 g, 112.9 mmol), dimethylformamide dimethyl acetal (40.3 g, 338.6 mmol) was refluxed under nitrogen for 1 hour. The reaction mixture was cooled, diluted with ethyl acetate (150 mL) and ether (150 mL). The solid was collected by filtration, triturated with a solution of ethyl acetate and hexane (1:1, 200 mL). Compound 8 was obtained as a red-orange solid (23.6 g, 101.6 mmol, 90%). GC/MS, m/z=232 at tR=15.11 min (100%). LC/MS, [M+H]′=233.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06958342B2 |
| 출처 데이터셋 | uspto-grants-2005_10 |
| ORD ID | ord-4658cafef4a24b5e87fc6808c8683331 |
| 출처 메모 | uspto-grants-2005_10 |