Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Acetamidobenzyl alcohol → N-(2-formylphenyl)acetamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Acetamidobenzyl alcohol | HCID 339292 | — |
| 촉매 | Manganese dioxide | HCID 14801 | — |
| 용매 | Chloroform | HCID 6212 | — |
| 생성물 | N-(2-formylphenyl)acetamide | HCID 326664 | 73% |
반응 단계
To a stirred solution of N-acetyl-2-amino-benzylalcohol (20 g) in dry CHCl3 (500 mL) was added MnO2 (160 g, 8 equivalents) and allowed to stir at room temperature for 12 h. The reaction mixture was filtered through celite and concentrated. The crude product was recrystallised from CHCl3/petrol ether to give N-acetyl-2-aminobenzaldehyde (14 g, 73%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07312358B2 |
| 출처 데이터셋 | uspto-grants-2007_12 |
| ORD ID | ord-6b72ab55819f44d887a00194ca641705 |
| 출처 메모 | uspto-grants-2007_12 |