참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | Dimethyl Sulfate | HCID 6497 | — |
| 반응물 | Potassium Hydroxide | HCID 14797 | — |
| 반응물 | 3,6-Dichlorosalicylic acid | HCID 18844 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | Dicamba | HCID 3030 | — |
반응 단계
2-Hydroxy-3,6-dichlorobenzoic acid (44.4 g) is dissolved in a solution of potassium hydroxide (11.2 g, 0.2 mole) and water (100 ml). The solution is heated to reflux (about 100° C.) and stirred vigorously while dimethyl sulfate (63.1 g, 0.5 mole) is added dropwise. The reaction mixture is then treated with a solution of potassium hydroxide (14.0 g, 0.25 mole) in 25.0 ml of water and refluxed for an additional 2 hours. The reaction mixture is then cooled and acidified to Congo red with hydrochloric acid to precipitate the desired 2-methoxy-3,6-dichlorobenzoic acid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US04161611 |
|---|
| 출처 데이터셋 | uspto-grants-1979_07 |
|---|
| ORD ID | ord-c60020878259412b8573d192325b9d4d |
|---|
| 출처 메모 | uspto-grants-1979_07 |
|---|
