Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Benzene → Bicyclo(3.1.0)hexan-2-one, 5-(1-methylethyl)-
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Benzene | HCID 241 | — |
| 반응물 | Dimethyl Sulfoxide | HCID 679 | — |
| 반응물 | Isopropanol | HCID 3776 | — |
| 반응물 | Sodium Hydroxide | HCID 14798 | — |
| 반응물 | Sulfoxonium, trimethyl-, iodide (1:1) | HCID 74498 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | Bicyclo(3.1.0)hexan-2-one, 5-(1-methylethyl)- | HCID 92784 | 42% |
반응 단계
25 ml of DMSO, 35 ml of benzene, 25 ml of isopropyl alcohol, 3.1 g (25 mM) of CP, 2.4 g (30 mM) of 50% aqueous sodium hydroxide and 5 ml of water were added to 6.9 g (31.25 mM) of trimethylsulfoxonium iodide and the reaction was carried out at room temperature for 5 hours. Then, the treatments were carried out as described in Example 8. 2.6 g (76% yield) of crude product were produced, from which1.45 g (42 % yield) of sabina ketone were obtained by distillation.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04162258 |
| 출처 데이터셋 | uspto-grants-1979_07 |
| ORD ID | ord-f188c799d94b41fb894a66beaaba8e2c |
| 출처 메모 | uspto-grants-1979_07 |