Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3-Amino-5-methyl-4H-1,2,4-triazole → HCID 178469337, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3-Amino-5-methyl-4H-1,2,4-triazole | HCID 234610 | — |
| 반응물 | 2-Butynedioic acid, monoethyl ester | HCID 71360575 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | HCID 178469337 | HCID 178469337 | 32.4% |
반응 단계
A suspension of 14.7 g of 3-amino-5-methyl-s-triazole and 26.8 g of ethyl acetylenedicarboxylate in 120 ml of ethanol was refluxed for three hours, the reaction mixture was allowed to stand at room temperature for one hour, and the formed crystals were collected by filtration. The filtrate was concentrated and the residue was recrystallized from dichloromethane, and the crystals were joined with those obtained above. Purification by silica gel chromatography gave 10.8 g of the objective compound as colorless crystals.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05064953 |
| 출처 데이터셋 | uspto-grants-1991_11 |
| ORD ID | ord-5371e796ddc745a7aca9b7704cf9d928 |
| 출처 메모 | uspto-grants-1991_11 |