Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrazine hydrate (1:1) → 4,5-Dihydro-5-methyl-6-(4-(4-oxo-1(4H)-pyridinyl)phenyl)-3(2H)-pyridazinone
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrazine hydrate (1:1) | HCID 24654 | — |
| 반응물 | 3-[4-(4-Oxo-1,4-dihydropyridin-1-yl)benzoyl]butanoic acid | HCID 9947748 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | 4,5-Dihydro-5-methyl-6-(4-(4-oxo-1(4H)-pyridinyl)phenyl)-3(2H)-pyridazinone | HCID 130702 | — |
반응 단계
Hydrazine hydrate (1.8 g) was added to a suspension of 3-[4-(4-oxo-1,4-dihydropyridin-1-yl)benzoyl]-butanoic acid (5 g) in water (60 ml). The resulting solution was stirred under reflux for 2 hours and cooled to afford the title compound as a pale yellow solid, 4.45 g. m.p. 255-258° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05066653 |
| 출처 데이터셋 | uspto-grants-1991_11 |
| ORD ID | ord-9c2afb1006004f7ca2329051ff5f23b2 |
| 출처 메모 | uspto-grants-1991_11 |