Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
N-Hydroxyphthalimide → N-(4-octyloxybenzyloxy)phthalimide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | N-Hydroxyphthalimide | HCID 10665 | — |
| 반응물 | Triphenylphosphine | HCID 11776 | — |
| 반응물 | p-Octyloxybenzyl alcohol | HCID 144261 | — |
| 반응물 | ethyl N-ethoxycarbonyliminocarbamate | HCID 220568 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | N-(4-octyloxybenzyloxy)phthalimide | HCID 19969096 | 83.4% |
반응 단계
Diethyl azodicarboxylate (18.4 g) was added dropwise to a suspension of 4-octyloxybenzyl alcohol (25 g), N-hydroxyphthalimide (17.15 g) and triphenylphosphine (27.74 g) in tetrahydrofuran (250 ml) under ice-cooling. The reaction mixture was stirred at room temperature for 2 hours, and evaporated in vacuo. The residue was purified by chromatography on silica gel to give N-(4-octyloxybenzyloxy)phthalimide (33.45 g) as crystals.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | USH0001638 |
| 출처 데이터셋 | uspto-grants-1997_03 |
| ORD ID | ord-e527255a53ed4f3889660a581d775414 |
| 출처 메모 | uspto-grants-1997_03 |