Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Potassium Carbonate → 3-(2,4,6-Triiodophenoxy)nonane
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | 2,4,6-Triiodophenol | HCID 11862 | — |
| 반응물 | 3-Nonanol | HCID 12216 | — |
| 반응물 | Methanesulfonate | HCID 85257 | — |
| 반응물 | 2-(2,4,6-Triiodophenoxy)pentadecane | HCID 15343309 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | 3-(2,4,6-Triiodophenoxy)nonane | HCID 19959848 | 67.3% |
반응 단계
The mesylate of 3-nonanol (11.5 g, 51.9 mmol), triiodophenol (24.5 g, 51.9 mmol) and potassium carbonate (7.18 g, 51.9 mmol) were reacted in dry DMF (200 ml) as per 2-(2,4,6-triiodophenoxy)-pentadecane except at an oil bath temperature of 87° C. for 16 hrs. The reaction was processed as for 2-(2,4,6-triiodophenoxy)-pentadecane to provide a light brown oil. Flash column chromatography (silica, hexanes) provided 3-(2,4,6-Triiodophenoxy)nonane (20.9 g, 67%) as a clear viscous oil.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05607660 |
| 출처 데이터셋 | uspto-grants-1997_03 |
| ORD ID | ord-8adec65c75924675a88dbe9001da7693 |
| 출처 메모 | uspto-grants-1997_03 |