Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HCID 178418361, 화합물 → Tetrahydro-6-(phenylmethyl)-1H-pyrrolo(3,4-b)pyridine-5,7(2H,6H)-dione
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | HCID 178418361 | HCID 178418361 | — |
| 반응물 | HCID 178524453 | HCID 178524453 | — |
| 촉매 | Ruthenium | HCID 23950 | — |
| 용매 | 2-Methoxyethanol | HCID 8019 | — |
| 생성물 | Tetrahydro-6-(phenylmethyl)-1H-pyrrolo(3,4-b)pyridine-5,7(2H,6H)-dione | HCID 9899604 | 90.1% |
반응 단계
47.6 g (0.2 mol) of pyridine-2,3-dicarboxylic acid N-benzylimide (British Patent 1,086,637; Chem. Abstr. 68, 95695w) are hydrogenated in 400 ml of glycol monomethyl ether over 15 g of ruthenium-on-active charcoal (5% strength) at 90° C. under 100 bar until the calculated amount of hydrogen has been taken up. The catalyst is then filtered off and the filtrate is concentrated on a rotary evaporator. 44 g of an oily crude product are obtained.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05607942 |
| 출처 데이터셋 | uspto-grants-1997_03 |
| ORD ID | ord-2843ce7880d846f0928fc66e8164ab5a |
| 출처 메모 | uspto-grants-1997_03 |