Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Acetone → 5,5-Bis(bromomethyl)-2,2-dimethyl-1,3-dioxane
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Acetone | HCID 180 | — |
| 반응물 | Water | HCID 962 | — |
| 반응물 | p-Toluenesulfonic acid | HCID 6101 | — |
| 반응물 | 2,2-Bis(bromomethyl)-1,3-propanediol | HCID 18692 | — |
| 용매 | Benzene | HCID 241 | — |
| 생성물 | 5,5-Bis(bromomethyl)-2,2-dimethyl-1,3-dioxane | HCID 14537228 | — |
반응 단계
A mixture of 10 g of 2,2-bis(bromomethyl)-1,3-propanediol, 5 ml of acetone and a catalytic quantity (0.1 g) of p-toluenesulfonic acid was heated under reflux in 150 ml of benzene until the theoretical amount of water (0.8 ml) had been collected in a Dean-Stark trap (2 hours). Evaporation of the solvent gave 5,5-bis(bromomethyl)-2,2-dimethyl-1,3-dioxane (6A), as a solid, m.p.: 56°-58° C. The purity according to gas-liquid chromatography and proton NMR was 99%.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04665197 |
| 출처 데이터셋 | uspto-grants-1987_05 |
| ORD ID | ord-994df256764a44c08adbb3675f3fd28f |
| 출처 메모 | uspto-grants-1987_05 |