huagongshe.com
HRID1033409

反应详情

EQUATION

反应方程式

HRID 1033409 的结构方程式

REACTANTS

反应物

2
结构：N[C@@H]1CCc2ccccc2NC1=O
HCID10103689

(3R)-3-Amino-1,3,4,5-tetrahydro-2H-1-benzazepin-2-one

C10H12N2O

结构：CC(C)(CNC(=O)OCc1ccccc1)C(=O)O
HCID14551010

未命名化合物

PRODUCTS

生成物

1
结构：CC(C)(CNC(=O)OCc1ccccc1)C(=O)N[C@@H]1CCc2ccccc2NC1=O
HCID18651458

未命名化合物

PROCEDURE

实验过程

Prepared from 3-(benzyloxycarbonylamino)-2,2-dimethylpropanoic acid and 3(R)-amino-2,3,4,5-tetrahydro-1H-[1]benzazepin-2-one (Example 1, Step E) by the procedure described in Example 1, Step F. 1H NMR (200MHz, CDCl3): 1.19 (s,6H), 1.90 (m,1H), 2.6-3.0 (n,3H), 3.26 (d,6Hz,2H), 4.46 (m,1H), 5.07 (s,2H), 5.7 (br t,1H), 6.62 (d,7Hz,1H), 6.97 (d,8Hz,1H), 7.1-7.3 (m,3H), 7.3 (s,5H), 8.14 (br s,1H). FAB-MS: calculated for C23H27N3O4 409; found 410 (M+H,100%).