反应详情

6-Bromo-2-methoxynaphthalene (5.9 g, 24.81 mmol, 1 eq) and NBS (4.41, 24.81 mmol, 1 eq) are boiled in 50 ml of THF under reflux for 2 h. After washing with 1 N HCl, the organic phase is dried over magnesium sulfate, filtered and concentrated in vacuum on a rotary evaporator. The compound is obtained in quantitative yield (7.8 g).

1. temperatureunder reflux for 2 h
2. washAfter washing with 1 N HCl
3. dry with materialthe organic phase is dried over magnesium sulfate
4. filtrationfiltered
5. concentrationconcentrated in vacuum on a rotary evaporator
6. customThe compound is obtained in quantitative yield (7.8 g)