反应详情

Following the procedure used to prepare {1-[4-(6-fluoro-4-oxo-2-phenyl-4H-chromen-3-yl)-phenyl]-cyclobutyl}-carbamic acid tert-butyl ester, 3-iodo-7,8-dimethoxy-2-phenyl-chromen-4-one (82 mg, 0.20 mmol) was reacted to give the title compound (41 mg, 41%). 1H NMR (400 MHz, CDCl3): δ 7.56-7.52 (d, 1H), 6.99-6.68 (m, 9H), 6.61-6.56 (d, 1H), 4.61-4.54 (m, 1H), 3.57-3.53 (m, 6H), 2.12-2.00 (m, 4H), 1.65-1.28 (m, 2H), 1.00-0.72 (m, 9H).

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