HRID1037216
反应详情
EQUATION
反应方程式
REACTANTS
反应物
PRODUCTS
生成物
PROCEDURE
实验过程
Following the procedure used to prepare 3-[4-(1-amino-cyclobutyl)-phenyl]-6-fluoro-2-phenyl-chromen-4-one, {1-[4-(4-oxo-2-phenyl-6-trifluoromethoxy-4H-chromen-3-yl)-phenyl]-cyclobutyl}-carbamic acid tert-butyl ester was reacted to give the title compound as a white solid (54 mg, 80%). 1H NMR (400 MHz, DMSO-d6): δ 7.97-7.87 (m, 3H), 7.45-7.32 (m, 7H), 7.16-7.12 (m, 2H), 2.42-2.33 (m, 2H), 2.15-2.05 (m, 2H), 2.05-1.94 (m, 1H), 1.70-1.60 (m, 1H). LCMS (Method E): RT=4.06 min, [M+H]+=452.
WORKUP
后处理
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