HRID1037224
反应详情
EQUATION
反应方程式
REACTANTS
反应物
PRODUCTS
生成物
PROCEDURE
实验过程
Following the procedure used to prepare 3-[4-(1-amino-cyclobutyl)-phenyl]-6-fluoro-2-phenyl-chromen-4-one, (1-{4-[6-methoxy-4-oxo-2-phenyl-7-(2H-pyrazol-3-yl)-4H-chromen-3-yl]-phenyl}-cyclobutyl)-carbamic acid tert-butyl ester was reacted to give the title compound as a pale yellow solid (34 mg, 75%). 1H NMR (400 MHz, DMSO-d6): δ 13.32-13.18 (br s, 1H), 8.21 (s, 1H), 7.88-7.72 (br s, 1H), 7.60-7.56 (br s, 1H), 7.44-7.30 (m, 7H), 7.19-7.14 (m, 2H), 6.97 (s, 1H), 4.01 (s, 3H), 2.45-2.36 (m, 2H), 2.20-2.10 (m, 2H), 2.08-1.97 (m, 1H), 1.72-1.61 (m, 1H). LCMS (Method E): RT=3.39 min, [M+H]+=464.
WORKUP
后处理
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