HRID1037298
反应详情
EQUATION
反应方程式
REACTANTS
反应物
PRODUCTS
生成物
PROCEDURE
实验过程
Following the procedure of 3-[4-(1-amino-cyclobutyl)-phenyl]-6-fluoro-2-phenyl-chromen-4-one, {1-[4-(2-methyl-6-oxo-8-phenyl-2,6-dihydro-9-oxa-1,2-diaza-cyclopenta[a]naphthalen-7-yl)-phenyl]-cyclobutyl}-carbamic acid tert-butyl ester was reacted to give the title compound as a white solid (16 mg, 83%). 1H NMR (400 MHz, DMSO-d6): δ 8.55 (s, 1H), 7.69 (d, J=8.7 Hz, 1H), 7.58 (d, J=8.7 Hz, 1H), 7.45-7.31 (m, 7H), 7.18 (d, J=7.7 Hz, 2H), 4.89 (bs, 2H), 4.24 (s, 3H), 2.48-2.35 (m, 2H), 2.22-2.12 (m, 2H), 2.05-1.94 (m, 1H), 1.72-1.59 (m, 1H). LCMS (Method E): RT=3.16 min, [M+H]+=422.
WORKUP
后处理
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