HRID1037428
反应详情
EQUATION
反应方程式
REACTANTS
反应物
PRODUCTS
生成物
PROCEDURE
实验过程
Following the procedure used to prepare 3-(4-(1-aminocyclobutyl)phenyl)-2-phenyl-8-(1,3,5-trimethyl-1H-pyrazol-4-yl)-4H-pyrano[2,3-c]pyridin-4-one, tert-butyl 1-(4-(8-(2-hydroxyethoxy)-4-oxo-2-phenyl-4H-pyrano[2,3-c]pyridin-3-yl)phenyl)cyclobutylcarbamate was reacted to give the title compound. (10 mg, 62%). 1H NMR (400 MHz, CD3OD): δ 8.15 (d, 1H), 7.55 (d, 1H), 7.49-7.31 (m, 9H), 4.68-4.65 (m, 2H), 3.95-4.01 (m, 2H), 2.82-2.75 (m, 2H), 2.63-2.52 (m, 2H), 2.30-2.19 (m, 1H), 2.03-1.92 (m, 1H). LCMS (Method I): RT=3.83 min, [M+2]+=430.
WORKUP
后处理
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