反应详情

3-[2-(4-{5-[1,1,1,3,3,3-Hexafluoro-2-(4-methoxybenzyloxy)propan-2-yl]-4-propylpyridin-2-yl}piperazin-1-yl)ethyl]-5-[4-(1-methylethoxy)phenyl]-5-methylimidazolidine-2,4-dione (10 mg, 0.0131 mmol) was dissolved in ethyl acetate (2 mL), added palladium carbon (1.0 mg), and the mixture was stirred at room temperature for 6 hours under a hydrogen atmosphere. The reaction solution was filtered through a pad of celite, and concentrated in vacuo. The title compound (7.3 mg (yield 86%)) was obtained as a yellow oil.

1. filtrationThe reaction solution was filtered through a pad of celite
2. concentrationconcentrated in vacuo