反应详情

The title compound was synthesized according to the procedure described in example 133 using 6-chloro-2-(3-oxo-cyclopentyl)-quinoline-5-carboxylic acid (1-hydroxy-3-methylcyclohexyl methyl)-amide, and dimethylamine. 1H NMR (400 MHz, DMSO-d6) δ ppm (VTNMR: 80° C.): 8.26-8.24 (m, 1H), 8.11-8.09 (m, 1H), 7.97-7.94 (m, 1H), 7.73-7.70 (m, 1H), 7.56-7.54 (m, 1H), 3.87-3.85 (m, 1H), 3.46-3.33 (m, 3H), 2.77-2.49 (m, 1H), 2.25-1.34 (m, 20H), 0.87-0.77 (m, 1H). m/z: 444.0 [M+H]+