反应详情

The title compound was prepared using the procedure described in Example 1G using 1-(4-acetyl-phenyl)-1H-pyridin-4-one for 1-(4-methyl-2-thiophen-2-yl-thiazol-5-yl)-ethanone. 1H NMR (300 MHz, CDCl3) δ 1.15 (d, J=6.10 Hz, 3H), 1.49 (m, 1H), 1.78 (m, 2H), 1.95 (m, 1H), 2.27 (m, 1H), 2.43 (m, 2H), 3.05 (m, 2H), 3.16 (m, 1H), 3.31 (m, 1H), 6.54 (d, J=7.80 Hz, 2H), 7.49 (d, J=8.48 Hz, 2H), 7.66 (m, 4H), 7.87 (d, J=8.81 Hz, 1H), 8.10 (d, J=8.48 Hz, 1H), 8.22 (d, J=8.48 Hz, 1H), 8.33 (d, J=8.48 Hz, 2H); MS (DCI-NH3) [M+H]+ at 410.