反应详情

The title compound was prepared using the procedure described in Example 1G using 1-(4-piperidin-1-yl-phenyl)-ethanone for 1-(4-methyl-2-thiophen-2-yl-thiazol-5-yl)-ethanone. 1H NMR (300 MHz, CDCl3) δ 1.14 (d, J=5.42 Hz, 3H), 1.70 (m, 10H), 2.24 (m, 1H), 2.39 (m, 2H), 3.01 (m, 2H), 3.14 (m, 1H), 3.29 (m, 5H), 7.04 (d, J=8.81 Hz, 2H), 7.56 (dd, J=8.48, 2.03 Hz, 1H), 7.59 (s, 1H), 7.80 (d, J=8.48 Hz, 1H), 8.01–8.10 (m, 4H); MS (DCI-NH3) [M+H]+ at 400.