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HRID1158332

反应详情

EQUATION

反应方程式

HRID 1158332 的结构方程式

REACTANTS

反应物

3
结构：CN
HCID6329

Methylamine

CH5N

结构：CC#N.O
HCID18373917

Acetonitrile--water (1/1)

C2H5NO

结构：COCCCOc1cc(C(=O)N(C[C@@H]2CN(C(=O)OC(C)(C)C)C[C@H]2C(=O)O)C(C)C)ccc1OC
HCID59512388

未命名化合物

PRODUCTS

生成物

1
结构：CNC(=O)[C@@H]1CNC[C@H]1CN(C(=O)c1ccc(OC)c(OCCCOC)c1)C(C)C
HCID11851629

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CC#N
溶剂HCID6342

Acetonitrile

C2H3N

PROCEDURE

实验过程

The title compound is prepared analogously as described for the title compound Example 1, starting from (3S*,4R*)-4-({isopropyl-[4-methoxy-3-(3-methoxy-propoxy)-benzoyl]-amino}-methyl)-pyrrolidine-1,3-dicarboxylic acid 1-tert-butyl ester and methylamine. MS (LC-MS): 422.1 [MH]+; tR (HPLC, nucleosil C18 column, 10-100% CH3CN/H2O/5 min, 100% CH3CN/3 min, flow: 1.5 ml/min): 3.83 min.

WORKUP

后处理

  1. customThe title compound is prepared analogously
  2. custom3.83 min.