反应详情

The title compound was prepared in a similar manner to that described in example 1 from 5-bromo-8-hydroxy-1,6-naphthyridine-7-carbonitrile (100 mg, 0.40 mmol) and phenylacetic hydrazide (120 mg, 0.80 mmol) to give a yellow solid (102 mg, 67%). 1H NMR (CDCl3/CD3OD): δ 9.03 (d, J=2.8 Hz, 1 H), 8.46 (d, J=8.0 Hz, 1 H), 7.62 (dd, J=8.4, 4.0 Hz, 1 H), 7.28-7.16 (m, 5 H), 4.12 (s, 2 H); MS m/z 382 (M+1).