HRID1176285

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：C=CCOc1ccc(C2CCN(C(=O)OC(C)(C)C)CC2O)cc1

HCID54331732

未命名化合物

HCID68504434

未命名化合物

PRODUCTS

生成物

结构：C=CCOc1ccc(C2CCN(C(=O)OC(C)(C)C)CC2OCc2ccc3c(c2)N(CCCOC)C(=O)CC3)cc1

HCID68497775

未命名化合物

PROCEDURE

实验过程

Analogously to Method D, 3.26 g of tert-butyl 4-(4-allyloxyphenyl)-3-hydroxypiperidine-1-carboxylate and 2.62 g of 7-chloromethyl-1-(3-methoxypropyl)-3,4-dihydro-1H-quinolin-2-one are reacted. The title compound is obtained as a slightly yellowish oil. Rf=0.16 (1:1 EtOAc-heptane); Rt=5.50.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-c57ef5d169e948e9a10ea12be96e6cb7
来源数据集: uspto-grants-2010_11
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07842688B2
来源说明: uspto-grants-2010_11

反应 SMILES

[CH2:1]([O:4][C:5]1[CH:10]=[CH:9][C:8]([CH:11]2[CH2:16][CH2:15][N:14]([C:17]([O:19][C:20]([CH3:23])([CH3:22])[CH3:21])=[O:18])[CH2:13][CH:12]2[OH:24])=[CH:7][CH:6]=1)[CH:2]=[CH2:3].Cl[CH2:26][C:27]1[CH:36]=[C:35]2[C:30]([CH2:31][CH2:32][C:33](=[O:42])[N:34]2[CH2:37][CH2:38][CH2:39][O:40][CH3:41])=[CH:29][CH:28]=1>>[CH2:1]([O:4][C:5]1[CH:6]=[CH:7][C:8]([CH:11]2[CH2:16][CH2:15][N:14]([C:17]([O:19][C:20]([CH3:23])([CH3:22])[CH3:21])=[O:18])[CH2:13][CH:12]2[O:24][CH2:26][C:27]2[CH:36]=[C:35]3[C:30]([CH2:31][CH2:32][C:33](=[O:42])[N:34]3[CH2:37][CH2:38][CH2:39][O:40][CH3:41])=[CH:29][CH:28]=2)=[CH:9][CH:10]=1)[CH:2]=[CH2:3]