HRID1177124

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：COC(=O)c1cc(Oc2ccc(C(=O)N(C)C)c(F)c2)c2c(c1)OC(C)(C)C2

HCID59560252

未命名化合物

结构：CC1(C)Cc2c(Oc3ccc(S(C)(=O)=O)cc3)cc(C(=O)O)cc2O1

HCID59560427

未命名化合物

PRODUCTS

生成物

结构：CN(C)C(=O)c1ccc(Oc2cc(C(=O)O)cc3c2CC(C)(C)O3)cc1F

HCID59560411

未命名化合物

PROCEDURE

实验过程

The title compound was prepared in a similar manner as described for Intermediate 15a, from 4-(4-dimethylcarbamoyl-3-fluoro-phenoxy)-2,2-dimethyl-2,3-dihydro-benzofuran-6-carboxylic acid methyl ester (142a). 1H NMR (400 MHz, CDCl3)) δ 7.40 (t, J=7.96 Hz, 1 H) 7.27-7.33 (m, 2 H) 6.80 (dd, J=8.34, 2.02 Hz, 1 H) 6.70 (dd, J=10.61, 2.27 Hz, 1 H) 3.10-3.18 (m, 3 H) 3.00 (br. s., 3 H) 2.92 (s, 2 H) 1.49 (s, 6 H); LCMS for C20H20FNO5 m/z 374.00 (M+H).