HRID1177238

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID15348

6-Amino-3-methylpyridine

C6H8N2

结构：CC(C)(C)OC(=O)c1cc(Oc2ccc(S(C)(=O)=O)cc2)c2c(c1)OC(C)(CO)C2

HCID59559858

未命名化合物

PRODUCTS

生成物

结构：Cc1ccc(NC(=O)c2cc(Oc3ccc(S(C)(=O)=O)cc3)c3c(c2)OC(C)(CO)C3)nc1

HCID59560044

未命名化合物

PROCEDURE

实验过程

The title compound was prepared in a similar manner as described for Example 200, from 2-hydroxymethyl-4-(4-methanesulfonyl-phenoxy)-2-methyl-2,3-dihydro-benzofuran-6-carboxylic acid tert-butyl ester (227d) and 5-methyl-pyridin-2-ylamine. 1H NMR (400 MHz, CDCl3) δ 8.60 (d, J=8.84 Hz, 1 H) 8.05 (s, 1 H) 7.92 (d, J=8.84 Hz, 3 H) 7.28 (s, 1 H) 7.24 (s, 1 H) 7.15 (d, J=8.84 Hz, 2 H) 3.76 (d, J=111.87 Hz, 1 H) 3.62 (d, J=111.87 Hz, 1 H) 3.22 (d, J=116.67 Hz, 1 H) 3.07 (s, 3 H) 2.83 (d, J=116.67 Hz, 1 H) 2.42 (s, 3 H) 1.47 (s, 3 H); LCMS for C24H24N2O6S m/z 469.00 (M+H)+.