反应详情

The title compound was prepared by dissolving 20 g of alpha,alpha-diphenyl-4-piperidineethanol in 40 mL of anhydrous trifluoroacetic acid and stirring for 15 minutes. The volatiles were removed under vacuum and the residue was partitioned between toluene and 2N sodium hydroxide solution. The organic layers were dried over sodium sulfate, evaporated, and the residue was crystallized from hexane to give 17.2 g (92%) of 4-(2,2-diphenylethenyl)piperidine, mp 98°-99° C. Anal. Calcd for C19H21N: C, 86.65; H, 8,.04; N, 5.32. Found: C, 86.35; H, 7.97; N, 5.26.

1. customThe title compound was prepared
2. customThe volatiles were removed under vacuum
3. customthe residue was partitioned between toluene and 2N sodium hydroxide solution
4. dry with materialThe organic layers were dried over sodium sulfate
5. customevaporated
6. customthe residue was crystallized from hexane