HRID1261529

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID2724141

Tetra-n-butylammonium fluoride

C16H36FN

结构：CCOC(=O)c1ccc(-c2ccc(OCCCO[Si](C)(C)C(C)(C)C)c(-c3ccc(N(CC)CC)c(CC)c3)c2)cc1

HCID66672171

未命名化合物

PRODUCTS

生成物

结构：CCOC(=O)c1ccc(-c2ccc(OCCCO)c(-c3ccc(N(CC)CC)c(CC)c3)c2)cc1

HCID11662917

未命名化合物

收率 53.5%

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID8028

Tetrahydrofuran

C4H8O

PROCEDURE

实验过程

In a manner similar to that of Example 2b, by reacting 660 mg of ethyl 4′-[3-(tert-butyldimethylsilanyloxy)propoxy]-4″-diethylamino-3″-ethyl[1,1′;3′,1″]terphenyl-4-carboxylate (1.1 mmol) in 25 mL of tetrahydrofuran with 1.2 mL of 1M tetrabutylammonium fluoride. 280 mg of ethyl 4″-diethylamino-3″-ethyl-4′-(3-hydroxypropoxy)-[1,1′;3′,1″]terphenyl-4-carboxylate are obtained (yield=52%).

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-d49d90b136ec4660bf94e8d84cdfbbf0
来源数据集: uspto-grants-2013_06
DOI: 10.6084/m9.figshare.5104873.v1
专利: US08470871B2
来源说明: uspto-grants-2013_06

反应 SMILES

[Si]([O:8][CH2:9][CH2:10][CH2:11][O:12][C:13]1[CH:18]=[CH:17][C:16]([C:19]2[CH:24]=[CH:23][C:22]([C:25]([O:27][CH2:28][CH3:29])=[O:26])=[CH:21][CH:20]=2)=[CH:15][C:14]=1[C:30]1[CH:35]=[CH:34][C:33]([N:36]([CH2:39][CH3:40])[CH2:37][CH3:38])=[C:32]([CH2:41][CH3:42])[CH:31]=1)(C(C)(C)C)(C)C.[F-].C([N+](CCCC)(CCCC)CCCC)CCC>O1CCCC1>[CH2:39]([N:36]([CH2:37][CH3:38])[C:33]1[CH:34]=[CH:35][C:30]([C:14]2[CH:15]=[C:16]([C:19]3[CH:20]=[CH:21][C:22]([C:25]([O:27][CH2:28][CH3:29])=[O:26])=[CH:23][CH:24]=3)[CH:17]=[CH:18][C:13]=2[O:12][CH2:11][CH2:10][CH2:9][OH:8])=[CH:31][C:32]=1[CH2:41][CH3:42])[CH3:40]