反应详情

Prepared by following a procedure analagous to Example 1255c by using 4-Chloro-3-(1-methyl-pyrrolidin-2-ylmethoxy)-phenylamine and N-tert-Butyl-3-(2-hydroxy-pyrrolo[2,1-f][1,2,4]triazin-7-yl)-benzenesulfonamide. 1H-NMR (DMSO) δ 9.8 (brs, 1H), 9.7 (s, 1H), 9 (s, 1H), 8.6 (s, 1H), 8.3 (d, J=8.0 Hz, 1H), 7.8 (d, J=8.0 Hz, 1H), 7.7 (t, 1H), 7.6 (s, 1H), 7.5 (d, J=8.7 Hz, 1H), 7.4 (m, 2H), 7.2 (d, J=4.7 Hz, 1H), 7.0 (d, J=4.7 Hz, 1H), 4.2 (m, 1H), 4.0 (m, 1H), 3.8 (m, 1H), 3.6 (m, 1H), 3.1 (m, 1H), 3.0 (s, 3H), 2.2 (m, 1H), 2.0 (m, 1H), 1.9 (m, 1H), 1.6 (m, 1H); LC/MS (ESI+): 569 (M+H).

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